Clinical Significance of Serum TNF-a and IL-6 Levels in Patients with Metabolic Syndrome

Elevated Serum Levels of IL-6 and TNF-α in Patients with Irritable Bowel Syndrome

Introduction: Irritable bowel syndrome (IBS) is accompanied by abdominal pain and intestinal discomforts. A line of evidence shows that the immune system plays important roles in the pathogenesis of the disease. Two main cytokines directing the immune system are IL-6 and TNF-α which may play a role in the immunopathogenesis of this disease. The present study aimed at investigating the serum lev...

Serum Levels of TNF-a, IL-6, and Selenium in Patients with Acute and Chronic Coronary Artery Disease

Background: Selenium (Se) is part of the glutathione peroxidase enzyme complex (GSH-PX) that plays an important role in antioxidant mechanisms in body, also it has been demonstrated that populations with low Se intake have 2-3 times greater risk of ischemic heart disease. Objective: To determine the circulating levels of IL- 6, TNF-α, Cu, Zn, and Se in patients with chronic coronary artery dis...

Serum Levels of TNF-α, TNF-αRI, TNF-αRII and IL-12 in Treated Rheumatoid Arthritis Patients

Background: Rheumatoid arthritis (RA) is a chronic multisystem autoimmune disease common in all races and ethnics. Cytokines and cytokines receptors play an important role in RA pathogenesis and clinical presentation. Objective: To investigate the serum levels of TNF-α, TNF-α RI, TNF-α RII and IL-12 in RA patients and healthy control group. Methods: In this study 43 patients fulfilling the revi...

Serum Adiponectin Level and Clinical, Metabolic, and Hormonal Markers in Patients with Polycystic Ovary Syndrome

Lipid Profile and Leptin Levels in Patients with Metabolic Syndrome

Abstract Background and Objective: Metabolic syndrome called a cluster of several metabolic disorders is associated with increased risk of cardiovascular diseases. Genetic differences in leptin receptor gene are related with the concentration and activity of leptin in that these discrepancies can influence lipid levels. We aimed to determine the association between the leptin receptor gene p...

serum levels of tnf-a, il-6, and selenium in patients with acute and chronic coronary artery disease

background: selenium (se) is part of the glutathione peroxidase enzyme complex (gsh-px) that plays an important role in antioxidant mechanisms in body, also it has been demonstrated that populations with low se intake have 2-3 times greater risk of ischemic heart disease. objective: to determine the circulating levels of il- 6, tnf-α, cu, zn, and se in patients with chronic coronary artery dise...